July 14, 2020

Search Results for: antibiotic resistant bacteria

Columbus State University Students Publish Breakthrough Study on Treating Antibiotic Resistant Bacteria

Columbus State University Biology Majors have published a paper about their research on treating antibiotic resistant bacteria. The students were focusing on alternative therapies to treat Acinetobacter haumannii, which causes urinary tract infections, pneumonia, burns and wound infections, and septicemia. The World Health Organization has said that antibiotic resistant bacteria is a major public health concern and may cause millions of deaths in the future because of untreatable common infections. And in 2016, the CDC found that antibiotic resistant Salmonella causes more than 6,000 illnesses in this country every year. Those types of infections are linked to beef, dairy, poultry, produce, and eggs. The paper, titled "The Effects of Antimicrobial Peptides WAM-1 and LL-37 on … [Read more...]

Scientists Find New Way to Fight Antibiotic Resistant Bacteria Through the Cell Wall

Antibiotic resistant bactéria are becoming a serious threat to human health. The CDC estimates that 2,000,000 Americans are sickened with antibiotic resistant bacterial infections every year, and 23,000 die. For instance, antibiotic resistant Salmonella causes at least 6,000 illnesses every year in this country. Those numbers will most likely increase over the next few years. But a new study published in PLOS Biology has found that bacterial cells have a weakness in the wall surrounding them that could be used to destroy them. Gram negative bacteria, such as E. coli, have a cell envelope that is made up of an outer and inner membrane. The two membranes are separated by an area that is called the periplasm. That double membrane in the cell wall makes the bacteria more resistant to … [Read more...]

Scientists Kill Antibiotic Resistant Bacteria with Brute Force

New research at University College London (UCL) has found that antibiotics can kill antibiotic-resistant bacteria with brute force. The study was published in Nature Scientific Reports. In order to kill bacteria, antibiotics have to bind to the cells in the pathogens. Bacterial resistance can be caused by molecular changes to the surface of the bacteria. Dr. Joseph Ndieyira of UCL Medicine said, "Antibiotics have 'keys' that fit 'locks' on bacterial cell surfaces, allowing them to latch on. When a bacterium becomes resistant to a drug, it effectively changes the locks so the key won't fit any more. Incredibly, we found that certain antibiotics can still 'force' the lock, allowing them to bind to and kill resistant bacteria because they are able to push hard enough. In fact, some … [Read more...]

OSU Scientists Make Progress in Antibiotic Resistant Bacteria War

Scientists at Oregon State University have made progress in the war against antibiotic resistant bacteria. More and more pathogenic bacteria are developing resistance against antibiotics, even our last-ditch drugs. Researchers have found that a molecule can neutralize bacteria's ability to become resistant to antibiotics. The study was published in the Journal of Antimicrobial Chemotherapy. This study is very important, since in September 2016, a woman in Nevada died from a bacterial infection that resisted every type of antibiotic we have in our arsenal. The death was reported by the Centers for Disease Control and Prevention last week. Scientists think that antibiotic-resistant bacteria will kill 10 million people by 2050. The molecule that the scientists at OSU constructed is … [Read more...]

Antibiotic Resistant Bacteria Reproduce Faster

A paper in the January 2017 edition of Nature Ecology & Evolution states that antibiotic-resistant bacteria grow faster and more efficiently than those that are not resistant to antibiotics. That is bad news in the fight against this deadly threat. Antibiotic resistant bacteria develop when the organisms are exposed to antibiotics. The drugs kill most of the bacteria, but some survive. And those that survive develop resistance to the drugs. Worse, they can pass that resistance on to other bacteria. The scientist from the University of Exeter were studying how E. coli bacteria develop resistance to antibiotics. In the study, they exposed the bacteria to doxycycline, a common antibiotic for treating infections. The bacteria quickly developed mutations for doxycycline … [Read more...]

Antibiotic Resistant Bacteria Found in Florida Sewage

According to the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota, antibiotic resistant bacteria has been found in Florida sewage. The bacteria was discovered in samples taken from water and sediment after a 2014 sewer-line spill that released 500,000 gallons of untreated wastewater into a St. Petersburg neighborhood. This information was published in Applied and Environmental Microbiology. The bacteria, Enterococcus faecium, is resistant to vancomycin, one of the "last resort" antibiotics we have to fight serious infections. That antibiotic has not been used for years because it has toxic side effects. But since more and more antibiotics are becoming less effective against infections, it is being brought back. And that vancomycin-resistant … [Read more...]

University of MN Identifies New Strain of Antibiotic Resistant Bacteria

Dr. Tim Johnson of the University of Minnesota has identified a new strain of antibiotic resistant bacteria. This bacteria, known as Enterobacter cloacae, was reported in a hospital outbreak in Fargo, North Dakota. Whole genome sequencing revealed that 32 of the strains collected from patients in the Upper Midwest were clonal. The bacteria is spreading throughout this region of the country. Dr. Johnson said, "this provides evidence for the origin of this multidrug resistant clone in the Fargo-Moorhead area, followed by its spread over time through nursing homes and hospitals in western Minnesota, and more recently in the Twin Cities metro area." He added, "this is a public health crisis. This is probably the biggest challenge we're going to face from a public health standpoint in our … [Read more...]

Antibiotic Resistant Bacteria Sickens 2 Million Americans Each Year

Antibiotic resistant bacteria sickens 2 million Americans each year, according to a new report from the Centers for Disease Control and Prevention (CDC). These infections contribute to more illness complications, higher health care costs and more intense treatments. The estimated cost of these illnesses is $20 billion annually in excess direct health care costs, with an additional $35 billion in lost productivity. One of the biggest drivers of this problem is inappropriate antibiotic prescribing by doctors, which can lead to adverse reactions. About 142,000 adult emergency department visits each year stem from adverse drug reactions from antibiotics, most of which are caused by allergies. The report states that doctors inappropriately prescribe antibiotics for acute respiratory tract … [Read more...]

White House Wants More Funding to Fight Antibiotic Resistant Bacteria

President Obama wants to increase federal funding to fight antibiotic resistant bacteria. The White House released a fact sheet this week detailing this investment to protect public health. The CDC estimates that every year at least 2,000,000 illnesses and 23,000 deaths are caused by antibiotic resistant bacteria in this country. These infections cost at least $20 billion in direct health-care costs and up to $35 billion in lost productivity and sick days. In September 2014, the President signed an Executive Order launching federal efforts to fight the increase in these bacteria, along with the National Strategy on Combating Antibiotic-Resistant Bacteria. The President's FY 2016 Budget nearly doubles the amount of Federal funding for combating and preventing antibiotic resistance … [Read more...]

Scientists Discover Achilles’ Heel in Antibiotic Resistant Bacteria

Scientists at the University of East Anglia may have discovered the Achilles' heel of antibiotic resistant bacteria. The research, published in the journal Nature, has found a defensive barrier that drug-resistant bacteria form around themselves. The gram negative bacteria, which include E. coli, form an impermeable lipid-based outer membrane that protects the organisms against attacks by the human immune system and antibiotics. Removing this barrier lets antibiotics kill the bacteria. The study found how the cells transport the barrier's building blocks, lipopolysaccharides, to the surface of the bacteria. Group leader Professor Changjiang Dong said in a statement, "we have identified the path and gate used by the bacteria to transport the barrier building blocks to the outer … [Read more...]

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